Most blood collection tubes contain an additive that either accelerates clotting of the blood clot activator or prevents the blood from clotting anticoagulant. A tube that contains a clot activator will produce a serum sample when the blood is separated by centrifugation and a tube that contains an anticoagulant will produce a plasma sample after centrifugation. Some tests require the use of serum, some require plasma, and other tests require anticoagulated whole blood. The table below lists the most commonly used blood collection tubes. Gel separates serum from cells.

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